Mu myaka icumi ishize, ubushakashatsi n’iterambere mu miti y’amaso byatumye habaho uburyo bushya bwo gutanga ibintu, nko gutera igihe cyo gutanga igihe hamwe na nanoparticles yinjira mu mucyo, bishobora kunoza imikorere y’ibiyobyabwenge, kugabanya ingaruka mbi, no kugabanya impungenge ziterwa no kubahiriza abarwayi b’ubuvuzi bw’amaso. .ibitonyanga.uburyo.
Indwara zo guhuza zifatwa nk'uburyo butanga ikizere, kandi ubu hakozwe iperereza ku ndwara ziterwa n'indwara, syndrome y'amaso yumye (DES), glaucoma, na allergie.imwe
Первая контактная линза с лекарственным покрытием, получившая одобрение FDA ранее в этом году (Acuvue Theravision с кетотифеном [Johnson & Johnson Vision]), представляет собой этафилкон А для ежедневного применения, обладающий противовоспалительными свойствами, обычно используемый в глазных каплях от аллергии. Lens ya mbere yashizwemo ibiyobyabwenge byemerewe na FDA mu ntangiriro zuyu mwaka (Acuvue Theravision hamwe na Ketotifen [Johnson & Johnson Vision]), ni etafilcon ya buri munsi Kurwanya inflammatory, bikunze gukoreshwa mubitonyanga byamaso.ketotifen.
Ibyamamare Byamamare Byinshi
Guhuza amakuru ni byiza nkibitonyanga amaso.2 Kubera ko ubu ari uburyo bushya bwo gushiramo, mugihe cyo kwiga ivuriro ryiyi lens, abo dukorana nanjye twakusanyije amakuru yinyongera kugirango yuzuye.
Twasesenguye ibizamini 2 byamavuriro hamwe na multicentre imwe yatunganijwe igenzurwa, yarimo abarwayi barenga 500.Ibisubizo, biherutse gusohoka muri Clinical and Experimental Optometry, bishushanya ishusho itanga abarwayi, abimenyereza, ndetse nigihe kizaza cyubuhanga.3
Gukoresha igihe kirekire ibitonyanga by'amaso bizwi ko biganisha ku biyobyabwenge biterwa na conjunctivitis - gutukura, gutwika no gutwika amaso nyuma yo kumara igihe kinini uhura n'ibigize ibitonyanga (cyane cyane birinda).bine
Uku kutoroherwa ntikubangamira gusa ibikorwa byumurwayi wa buri munsi nubuzima bwiza, ahubwo binabuza umurwayi gukomeza gukoresha ibitonyanga byamaso kuko umurwayi adashaka kongeramo ibitonyanga byamaso kumaso yamaze kurakara.5
Iyo umurwayi afite ubu burwayi, kwanduza corneal akenshi byerekana guhungabanya ubusugire bwa epitelium ya corneal, byerekana ko kuvura bigomba guhinduka kugirango ijisho rikire kandi birinde kwangirika.
Kwirinda guhura n’imiti ikaze, nkamaso yangiritse ya allergie, ni ngombwa cyane cyane kugabanya conjunctivite iterwa nibiyobyabwenge.
Kunywa inshuro nyinshi akenshi bisabwa kubera ko ibitonyanga byamaso bifite bioavailable nkeya - 5-10% gusa yibiyobyabwenge biboneka hejuru yijisho6 - kandi bigahita byogejwe no guhumbya no kumera.
Imiti ikoresheje imiti itanga imiti itanga inyungu nyinshi zishobora gukuraho bimwe mubibazo bifitanye isano no gutonyanga amaso, harimo:
Ibiyobyabwenge byongewe mumurongo mugihe cyo gukora, birimo intambwe yo guhagarika autoclave.Kubwibyo, ntibakenera kubika ibintu nka BAC, bisenya isano iri hagati ya selile epithelia selile.Buri lens itanga urugero rwiza rwibiyobyabwenge.
Ibikoresho bifata imiti bitanga imiti mu masaha, bityo bikaguma hejuru yijisho igihe kirekire kuruta ibitonyanga byamaso bikaraba vuba.Ikwirakwizwa rishingiye ku gusohora umwirondoro wa lensike yo guhuza ibemerera gutanga dosiye ihamye aho kuba inshuro nyinshi zisabwa kubitonyanga by'amaso.
Muguhuza ubuvuzi hamwe no gukosora iyerekwa muri etafilcon Yoroheje yo guhuza abantu, abarwayi ntibakeneye gutekereza kuri gahunda yimiti.Iyi ninyungu itanga icyizere kubarwayi bibagora kuguma kuri gahunda.
Umuti uhuza imiti ushobora gukemura ibibazo bimwe na bimwe bifitanye isano no gutonyanga amaso, ariko ikibazo gikurikiraho cy’inzobere mu kwita ku jisho ni iki: “Ni izihe ngaruka ziterwa no kwambara buri munsi imiti y’imiti hejuru yijisho?”
Ibyamamare Byamamare Byinshi
Jye na bagenzi banjye twasesenguye amakuru yavuye mu bigeragezo bibiri by’umutekano by’amavuriro byamaze ibyumweru 12 kandi harimo 560 bambara lens.Abarwayi 374 bambaye lensisiti yipimisha naho abarwayi 186 bambara lensbo.
Cornea yandujwe na fluorescein yakorewe kuri baseline hanyuma nyuma yibyumweru 1, 4, 8, na 12 bya lens kwambara.Nta tandukanyirizo rishingiye ku mibare ryagaragaye mu kwanduza itsinda ryitwa lens lens hamwe nitsinda rya placebo igihe cyose wasuye (95.86% na 95.88% icyiciro cya 0, mubyumweru 12).Ikirangantego cyose cyari cyoroshye cyangwa ibimenyetso.
Nyuma yibyumweru 4 byo kwambara, ayo matsinda yombi yagize igabanuka ryo kugabanuka kwa corneal yanduye kuva kuri baseline.Ihinduka rigaragara rishobora guterwa nabarwayi bahinduye mumurongo wabo usanzwe bajya mubintu bishya (etafilcon A, ifite amazi menshi7) na / cyangwa uburyo bwo kwambara (rimwe kumunsi, bivana ikigereranyo muburinganire) ibisubizo by'ibisubizo).Kubahiriza lensisiti yo kwiga byari bisa mumatsinda yombi (hafi 92%).
Mu gusoza, mu bushakashatsi bunini, bugenzurwa neza, buhumye-buhumye bw’ubuvuzi, dushobora kwemeza twizeye ko iyi lens ya antihistamine irekura idahindura cyane ubusugire bwa epitelium ya corneal.
Amaso yambaye utwo turangantego two guhuza ibiyobyabwenge ntagomba gutandukana nandi jisho ryambaye imiti itavura imiti, kikaba ari ikintu cyingenzi cyo kwishyira hamwe mubikorwa byuburyo.
Nta tandukaniro riri muburyo bwo guhuza lens cyangwa gusuzuma icyerekezo.Abarwayi bakeneye kumenya byinshi kuri lens kugirango babone icyerekezo bashaka kandi babone ubufasha bwinshi muri allergie y'amaso.
Ibimenyetso byerekana ko kongeramo antihistamine bitongera kwangirika kwa corneal epithelia ugereranije ninzira zisanzwe ziterana birashimishije mugihe dutegereje ko hashyirwa mubikorwa uburyo bushingiye ku biyobyabwenge.
Igihe cyo kohereza: Kanama-18-2022
